Top 10 connectivity.brain-map.org Wettbewerber

alleninstitute.org

Visit our purpose-built headquarters in Seattle to learn from scientists and educators about our big, team, and open science approach.

brainhq.com

Think faster, focus better, and remember more with BrainHQ—Improve your brain health with clinically proven brain training exercises.

jax.org

2024 Computational Sciences Publications

eneuro.org

Recently developed probes for extracellular electrophysiological recordings have large numbers of electrodes on long linear shanks. Linear electrode arrays, such as Neuropixels probes, have hundreds of recording electrodes distributed over linear shanks that span several millimeters. Because of the length of the probes, linear probe recordings in rodents usually cover multiple brain areas. Typical studies collate recordings across several recording sessions and animals. Neurons recorded in different sessions and animals thus have to be aligned to each other and to a standardized brain coordinate system. Here, we evaluate two typical workflows for localization of individual electrodes in standardized coordinates. These workflows rely on imaging brains with fluorescent probe tracks and warping 3D image stacks to standardized brain atlases. One workflow is based on tissue clearing and selective plane illumination microscopy (SPIM), whereas the other workflow is based on serial block-face two-photon (SBF2P) microscopy. In both cases electrophysiological features are then used to anchor particular electrodes along the reconstructed tracks to specific locations in the brain atlas and therefore to specific brain structures. We performed groundtruth experiments, in which motor cortex outputs are labeled with ChR2 and a fluorescence protein. Light-evoked electrical activity and fluorescence can be independently localized. Recordings from brain regions targeted by the motor cortex reveal better than 0.1-mm accuracy for electrode localization, independent of workflow used.

biodigital.com

BioDigital offers the world’s largest library of 3D anatomy content, all customizable and accessible in VR, AR, and on any desktop or mobile device.

pubmed.ncbi.nlm.nih.gov

Deng Z - Search Results - PubMed

nature.com

Nature is the foremost international weekly scientific journal in the world and is the flagship journal for Nature Portfolio. It publishes the finest ...

scalablebrainatlas.incf.org

open access to more than twenty brain atlases (mouse, rat, macaque, human, marmoset, ferret, possum), in an interactive 2d and 3d presentation.

ebrains.eu

Subscribe to the EBRAINS newsletter. Get the latest updates on neuroscience research, events, new tools, and infrastructure developments.