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10 Vials Per Box Disclaimer: The products mentioned are not intended for human or animal consumption. Research chemicals are intended solely for laboratory experimentation and/or in-vitro testing. Bodily introduction of any sort is strictly prohibited by law. All purchases are limited to licensed researchers and/or qualified professionals. All information shared in this article is for educational purposes only. This product is strictly for research/laboratory use only. Human or animal use and/or consumption is strictly prohibited by law. Only qualified and licensed professionals should handle these products. Any information found on Peptide Supply Co is strictly for educational purposes only. Refer to our terms and conditions for more details.

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Ipamorelin + CJC-1295 — Complementary GH Axis Research Blend This combo pairs Ipamorelin (a selective ghrelin/GHSR-1a agonist) with CJC-1295 (a GHRH analogue, ±DAC). Together they’re used to study pituitary growth-hormone (GH) pulsatility, hypothalamic–pituitary regulation, and downstream IGF-1 biology in controlled research settings. Component A — Ipamorelin CAS: 170851-70-4  PubChem CID: 9831659  Sequence (pentapeptide): Aib-His-D-2-Nal-D-Phe-Lys-NH2  Notes: Highly selective for GH release with minimal ACTH/cortisol or prolactin effects vs older GHRPs.  Component B — CJC-1295 (GHRH analogue) Forms: CJC-1295 with DAC (albumin-binding “Drug Affinity Complex”) and CJC-1295 no DAC / Mod GRF(1-29). CAS (reported): with DAC 446262-90-4 ; no-DAC listings vary by substitution, commonly 446036-97-1 or 863288-34-0.  Mechanism: Agonist at the GHRH receptor (GHRHR) on pituitary somatotrophs. PK note: DAC prolongs half-life via albumin binding; no-DAC behaves like short-acting GHRH(1-29) analogues. Why Use the Combo (Plain English) Two switches, one output: CJC-1295 triggers the pituitary via GHRH, while Ipamorelin stimulates the ghrelin/GHSR pathway. Hitting both can amplify GH pulses vs either alone (synergy shown with GHRH + GHRPs/ghrelin).  Clean signal: Ipamorelin is noted for selective GH release with low cortisol/prolactin cross-activation in studies—helpful for tidy readouts.  Design flexibility: Choose no-DAC (short-acting pulses) or DAC (sustained exposure) to match your protocol window. Key Study Themes — What’s Typically Tested GHRH + GHS synergy on GH pulsatility What’s tested: Co-administration of a GHRH analogue with a ghrelin mimetic; serial GH sampling and deconvolution analysis. What changes: Greater peak GH and area-under-curve vs either agent alone in human and animal models.  Why it matters: Models how dual hypothalamic inputs coordinate pituitary output, informing endocrine physiology and test paradigms.  Selectivity &am

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