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The prescription DHT blocker finasteride has been found to increase the risk of suicidal thoughts by the European Medicines Agency (EMA)1. The EMA reviewed recent research and has confirmed that increased suicidal thoughts is a side effect of finasteride 1mg and 5mg tablets. Finasteride works by blocking the enzyme 5-alpha-reductase from converting testosterone to dihydrotestosterone (DHT). DHT is known to cause hair loss so the use of prescription DHT blockers helps lower the levels of DHT from causing hair loss. Aside from causing hair loss, DHT also has roles in the brain as a neurosteroid. It supports the development of the hippocampus which is the center for memory, spatial navigation, learning, and emotional processing. Do natural DHT blockers like saw palmetto have the same side effect? For natural DHT blockers like saw palmetto to have the same effect as prescription DHT blockers like finasteride and dutasteride, they would need to lower DHT levels in the blood and brain to be able to affect mood and emotions. One paper comparing the effects of finasteride and saw palmetto on DHT levels2 found several studies in which saw palmetto did not lower DHT in the blood (serum) compared to finasteride. While it is possible, it is unlikely that natural DHT blockers like saw palmetto will cause an increase in suicidal  thoughts. For saw palmetto to lower DHT levels in the brain, it would have to lower DHT levels in the blood. For it to lower DHT levels in the brain, it would also have to cross the blood-brain barrier. Sources: https://www.ema.europa.eu/en/news/measures-minimise-risk-suicidal-thoughts-finasteride-dutasteride-medicines https://silvershell.com.tr/wp-content/uploads/2022/08/Ref.-8.-Marks-et-al-2001.pdf

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Effective September 30, 2020 Welcome to Perelel. We provide access to the www.perelelhealth.com website, “the Site”, sell our products to you and offer other services to you (collectively, “Products”), subject to the conditions set out on this page.  The Site and the Products are collectively referred to as the “Servic

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bustbunny.com

This Agreement is between Bust Bunny and you (“you” or “Customer”). This section sets forth the terms and conditions that apply to your use of the Bust Bunny Sites (defined below) and any products or services offered for sale by Bust Bunny and its affiliates (collectively, “Bust Bunny”). The right to use any product or

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If it feels like everyone is sick right now, you are not imagining it. This has been a particularly gnarly cold and flu season. The “what is going around?” carousel is spinning fast, and people are getting hit harder, staying sick longer, or bouncing from one thing to the next. Here is the good news: you have more cont

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foodology-global.com

Coleology Starter Diet Kit with Drink Mix PRO for mornings and Cutting Jelly for afternoons in a 10-day bundle. Supports metabolism, digestion, and weight balance.

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Um compromisso inabalável com a transparência nutricional. Para nós, a honestidade é a base de tudo que fazemos. Nosso lema, "Verdade em cada cápsula", reflete nosso esforço para garantir que nossos consumidores sempre saibam exatamente o que estão consumindo e na melhor forma existente para esse suplemento.