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RESUMO CONTEXTO: Diferenças de sexo e gênero são muitas vezes negligenciadas no desenho da...

pubmed.ncbi.nlm.nih.gov

Gates Foundation, St Jude Children's Research Hospital.

scholar.google.com.br

google scholar provides a simple way to broadly search for scholarly literature. search across a wide variety of disciplines and sources: articles, theses, books, abstracts and court opinions.

archivesofrheumatology.org

Background/Aims: This study aimed to investigate the relationship between obesity indices and non-alcoholic fatty liver disease (NAFLD) in patients with ankylosing spondylitis (AS). Materials and Methods: A total of 170 patients with AS were included in this observational study with both prospective and retrospective components. Anthropometric measurements (height, weight, waist circumference [WC]) were prospectively recorded by the investigators during routine clinical visits. Obesity indices, including body mass index (BMI), WC, and waist-to-height ratio (WHtR), were calculated. Non-alcoholic fatty liver disease was diagnosed based on existing abdominal ultrasonography reports. Laboratory data, including liver enzymes, lipid profiles, and inflammatory markers, were retrospectively collected. The diagnostic performance of WC for NAFLD was assessed using receiver operating characteristic (ROC) curve analysis. Results: Non-alcoholic fatty liver disease was detected in 57% of AS patients. Higher BMI and WHtR were significantly associated with both the prevalence and severity of NAFLD (P < .001). Patients with NAFLD exhibited significantly higher levels of C-reactive protein, triglycerides, and alanine aminotransferase, as well as lower high-density lipoprotein levels, compared to those without NAFLD (P < .05). Additionally, the aspartate aminotransferase/alanine aminotransferase ratio was <1 in 66% of NAFLD patients, suggesting its potential as a biochemical marker for NAFLD in AS. The ROC analysis identified WC cutoff values of 100 cm for males and 90 cm for females, demonstrating high sensitivity and specificity in predicting NAFLD. Conclusion: Obesity is strongly associated with NAFLD in AS patients. Body mass index and WHtR may serve as valuable indicators for assessing hepatic steatosis risk. Routine metabolic evaluations, including obesityrelated parameters and liver enzyme levels, could facilitate the early detection of NAFLD in AS patients. Further prosp

suntor.com.br

Introdução: No universo das clínicas de transição de cuidados, a atenção para com o bem-estar e a nutrição dos pacientes emerge como um dos pilares mais significativos. A Suntor Clínica de Transição, ciente da importância desses aspectos, incorpora em sua filosofia a implementação de uma terapia nutricional individualizada, visando à otimização da saúde física e […]

hermespardini.com.br

um dos melhores laboratórios da américa latina para realizar os seus exames, testes e vacinas!

sensceclinicspa.com.br

A Essence surgiu a partir da convicção que sobrepeso ou obesidade são doenças ou condições causadas por uma série de fatores e por isso precisam ser tratadas

endopelvic.com

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