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smj.org.sa

Objectives: To establish and maintain a comprehensive, up-to-date registry of juvenile idiopathic arthritis (JIA) cases, and to outline the methodology used in creating it. Methods: Retrospective and prospective data collection commenced in August 2021, using the Hospital Information System to identify electronic medical records of JIA patients. All individuals diagnosed with JIA and receiving follow-up care at King Abdullah Specialized Children’s Hospital (KASCH) in Riyadh were included. A broad range of variables covering sociodemographic characteristics, clinical features, laboratory results, imaging findings, and therapeutic medications were recorded in the REDCap platform. Data collection update occurs every 6 months. Results: By December 2024, the registry included 240 patients. The median age at presentation was 8 years (IQR: 4–11). Most patients (79%) were from the central region of Saudi Arabia, while the remainder were distributed across other regions. Oligoarthritis was the most common subtype (32.9%), followed by systemic JIA (25.8%). Among the biologic agents used to treat JIA, anti-TNF agents were the most frequently administered (62.5%), followed by anakinra (17%) and tocilizumab (13%). Conclusion: The JIAR-KASCH provides an in-depth profile of JIA epidemiology, clinical presentation, and management in Saudi Arabia. It also provides a framework that can guide the development of similar national registries, particularly in pediatric rheumatology, facilitating robust data collection and long-term disease monitoring.

pulsus.com

Open access medical research journals. Pulsus Group, the medical peer-review publisher, publishes the work of medical researchers in a manner

jamc.ayubmed.edu.pk

j ayub med coll abbottabad, the printed and online journal of ayub medical college abbottabad pakistan, is an indexed journal, recognised by pakistan medical and dental council(pm&dc) as a standard medical journal and by the higher education commission (hec) of pakistan.

sciepublish.com

Photocatalytic-induced cleaving of the ether C–O bond in model lignin compounds was studied with a closely-coupled compo-site material consisting of Ni(OH)2 and gold nanoparticles (NPs) on a zirconia support (Au/ZrO2–Ni(OH)2). The three important ether bond types consisting of α-O-4, β-O-4, and 4-O-5 linkages can all be cleaved using this catalyst at reaction temperatures 40, 85 and 95 °C when under low-flux visible light irradiation. The Au NPs action as a light-harvesting antenna provided light-generated hot electrons that reduced Ni2+ to Ni0. The Ni0 was the active catalytic site where reductive cleavage of ether C–O bonds occurred while it was oxidized to Ni2+ to complete the catalysis cycle. The plasmonic antenna system with supported Ni(OH)2 exhibited better ability for the catalytic reductive ether cleavages under visible light irradiation compared to photocata-lysts of Au NPs and Ni2+ ions immobilized on alumina fibers.

heartcc.com

Discover top-notch heart care services & AI tools. Stay updated! Learn more. Contact

predictomes.org

A free interactive resource for viewing predicted AlphaFold multimer structures for protein pairs in biological pathways.