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litfl.com

Does adrenaline require resuscitation or is adrenaline good for resuscitation? Gavin Perkins takes us through the research and findings.

medscape.com

today on medscape : get the latest medical news, clinical trial coverage, drug updates, journal articles, cme activities & more on medscape. a free resource for physicians.

thelancet.com

the best science for better lives. explore the latest high-quality research from the lancet group

clinicaltrials.gov

ClinicalTrials.gov is a website and online database of clinical research studies and information about their results

jamanetwork.com

Stay up to date, maintain your CME with the latest research, author interviews, apps, and learning courses from JAMA and the Specialty Journals.

dovepress.com

An international, peer reviewed, open access, online journal that welcomes laboratory and clinical findings in the fields of pain research and the prevention and management of pain. Original research, reviews, symposium reports, hypothesis formation and commentaries are all considered for publication.

medrxiv.org

Self-determination has been assessed as an internal psychological construct. External factors may also affect self-determination, but opportunities to make choices and decisions remain understudied. We developed and evaluated the AASPIRE-Choices and Decisions Scale (AASPIRE-CDS), a new measure of autistic adults’ opportunities to make choices and decisions, using a community-based participatory approach. We created and refined the AASPIRE-CDS through an iterative process. Data, from the AASPIRE Outcomes Project, included 839 autistic adults participating through direct report, supported direct report, and caregiver report (CR). Exploratory and confirmatory analyses supported a unidimensional structure. Measurement invariance analyses supported configural, metric, and partial scalar invariance across report type without CR, and across living status, with and without CR. The AASPIRE-CDS showed high internal consistency, test-retest reliability, and preliminary responsiveness to change over time. Convergent validity analyses showed that higher AASPIRE-CDS scores were associated with greater self-determination and communication fluency, more independent living, and fewer support needs. The AASPIRE-CDS showed weaker (albeit significant) associations with quality of life, overall health, and employment satisfaction than the self-determination measure showed with these variables. This pattern suggests that opportunities for choice-making are related to, but distinct from, commonly used measures of self-determination. Findings support the AASPIRE-CDS as a valid and reliable measure of choice-making opportunities in autistic adults across support needs but suggest caution interpreting CR. They underscore the importance of supporting autistic adults’ choice-making and evaluating opportunities for choice alongside internal self-determination. Future research should use larger CR samples to examine the validity of caregiver-reported choice-making opportunities. Lay Summary Sel

journals.asm.org

american society for microbiology (asm) journals deliver up-to-date and authoritative coverage of both basic and clinical microbiology. join our authors.