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tctmd.com

Guidelines still contain strong recommendations for aspirin’s use, but some are calling for new trials to confirm benefits.

ijcaonline.org

international journal of computer applications (ijca), issn 0975-8887, is a peer-reviewed journal published by foundation of computer science (fcs). the journal publishes original papers at the forefront of applied information systems that advance the field and that enhance exchange of innovative ideas between academicians and industrialists.

eneuro.org

Recently developed probes for extracellular electrophysiological recordings have large numbers of electrodes on long linear shanks. Linear electrode arrays, such as Neuropixels probes, have hundreds of recording electrodes distributed over linear shanks that span several millimeters. Because of the length of the probes, linear probe recordings in rodents usually cover multiple brain areas. Typical studies collate recordings across several recording sessions and animals. Neurons recorded in different sessions and animals thus have to be aligned to each other and to a standardized brain coordinate system. Here, we evaluate two typical workflows for localization of individual electrodes in standardized coordinates. These workflows rely on imaging brains with fluorescent probe tracks and warping 3D image stacks to standardized brain atlases. One workflow is based on tissue clearing and selective plane illumination microscopy (SPIM), whereas the other workflow is based on serial block-face two-photon (SBF2P) microscopy. In both cases electrophysiological features are then used to anchor particular electrodes along the reconstructed tracks to specific locations in the brain atlas and therefore to specific brain structures. We performed groundtruth experiments, in which motor cortex outputs are labeled with ChR2 and a fluorescence protein. Light-evoked electrical activity and fluorescence can be independently localized. Recordings from brain regions targeted by the motor cortex reveal better than 0.1-mm accuracy for electrode localization, independent of workflow used.

gmd.copernicus.org

Abstract. We have developed an open-source ray-tracing tool for space geodetic techniques. The software uses the geometric optics approximation to calculate the signal travel time delay induced by the atmosphere between two given points. The software called DNS (“Direct Numerical Simulation of signal travel time delay”) is written in Fortran and uses OpenMP to speed up computation. The input to the ray-tracing tool is 3D pressure, temperature and humidity fields. The Earth's magnetic field and electron density field are optional. For the neutral atmosphere (troposphere) the software accepts the NetCDF files from the atmospheric reanalysis ERA5 and the mesoscale model WRF. For the ionosphere the software accepts electron density fields derived from IRI and NeQuick. We review the current status of the software and test its performance. For example, the one-to-one comparison with the open-source software RADIATE shows the high speed and precision of our ray-tracing tool. We also show how our tool can be used to study higher-order ionospheric effects (L-band frequencies). The two outstanding features of the ray-tracing tool compared to previous model developments, i.e. the ability to handle both the troposphere and the ionosphere and do so efficiently, make it perfectly suited for geoscientific applications.

primescholars.com

Prime Scholars is an academic international peer-reviewed Journal with Prime Scholars is an academic international Open Access Publishing House

pubmed.ncbi.nlm.nih.gov

Bill & Melinda Gates Foundation.

sciencedirect.com

sciencedirect is the world's leading source for scientific, technical, and medical research. explore journals, books and articles.

magiran.com

بانک اطلاعات نشریات کشور، بزرگترین پایگاه مرجع و نمایشگاه دائمی مطبوعات ایرانی است که از سال 1380 تا کنون فعالیت می‌کند. اطلاعات، فهرست مطالب و متن بیش از سه هزار ژورنال و مجله علمی، تخصصی و عمومی ایرانی و چندین روزنامه سراسری معتبر در این سایت نمایه می‌شود.