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nevro.com

We Believe True Innovation Transforms More Lives

neuropace.com

The NeuroPace RNS System is the only FDA-approved epilepsy device that delivers personalized treatment by responding to abnormal brain activity and provides EEG data that can help improve patient care.

neuroelectrics.com

Unlocking the power of computational neuroscience to treat brain disorders. Our mission at Neuroelectrics is to improve the lives of people living with brain disease by delivering personalized brain stimulation therapy anywhere and at any time.

terumoneuro.com

Explore opportunities to join Terumo Neuro, a company dedicated to innovation in neurovascular care. Make an impact in brain aneurysm and stroke treatment.

remede.zoll.com

Central sleep apnea (CSA) is a serious condition that disrupts sleep and is linked to worsening cardiovascular outcomes

neurostar.com

Considering TMS therapy for depression? Asking the right questions can help you feel confident, informed, and prepared before beginning treatment.

barostim.com

CVRx® is always looking for talented and motivated individuals who have a passion for improving the lives of our patients. See our current openings.

ceribell.com

Learn more about how Ceribell helps patients and medical professionals by watching Clarity AI For 24/7 EEG Monitoring Alert - Manuscript Review With Dr. Josef Parvizi

vagustim.io

Background: The anti-inflammatory impacts of stimulating the vagus nerve as a part of the gut-brain axis on intestinal macrophage activity and inflammatory cytokine production have been documented. While vagus nerve stimulation until now has been chiefly invasive, non-invasive auricular vagus nerve stimulation (NitaVNS) has no adverse effects associated with invasive stimulation. The NitaVNS-mediated activation of brainstem nuclei can exert anti-inflammatory effects directly on the colon or indirectly through the spleen via a macrophage-acetylcholine-dependent pathway. Methods: Thirty C57BL/6 mice aged 11 to 12 weeks were divided into four groups: control (CTRL)-NitaVNS, CTRL-Sham, dextran sulphate sodium (DSS)-NitaVNS and DSS-Sham. Pre-set stimulation parameters (10 minutes duration, 10 V voltage, 500 s pulse width, and 20 Hz frequency) were applied for NitaVNS or sham-paw stimulation. 5% DSS was administered to induce colitis for five consecutive days, whereas CTRL mice received regular water. Weight loss, stool consistency, blood in the feces, and disease activity index were evaluated daily. Rectal bleeding, colon bleeding, and fecal consistency were determined as a composite macroscopic score upon sacrifice. Collected colon and blood samples were assessed for pro-inflammatory parameters such as interleukin (IL)-1β, tumor necrosis factor (TNF)-α, IL-6, C-reactive protein (CRP), matrix metalloproteinase (MMP)-2, macrophage inflammatory protein (Mip)-1α and β, and anti-inflammatory cytokine tumor growth factor (TGF)-β using qRT-PCR and ELISA. Results: Compared to colitic-sham mice, colitic NitaVNS mice demonstrated a delayed onset and a significantly lower clinical disease severity. Colitis induced significant weight loss, rectal bleeding, and stool consistency loss, and NitaVNS significantly abolished these effects. In colitic conditions, NitaVNS decreased the disease activity index significantly compared to the colitic sham group. Colitis increased the macroscopi

gladiatortherapeutics.com

Speed up chronic wound healing and physical recovery with Gladiator Therapeutics' medical devices that use far infrared technology.