Top 10 mackenziemathislab.org Wettbewerber

braininitiative.org

In 2020, BRAIN researchers continued to create new, state-of-the-art technology. We also witnessed advances in open science and data availability – movements that benefit of the entire scientific community. Here, we will look back on the year 2020, as well as look ahead to what the world of neuroscience is bringing in 2021. Looking Back… […]

open-neuroscience.com

Open Neuroscience is a user led repository of open source projects for neuroscience

eneuro.org

Recently developed probes for extracellular electrophysiological recordings have large numbers of electrodes on long linear shanks. Linear electrode arrays, such as Neuropixels probes, have hundreds of recording electrodes distributed over linear shanks that span several millimeters. Because of the length of the probes, linear probe recordings in rodents usually cover multiple brain areas. Typical studies collate recordings across several recording sessions and animals. Neurons recorded in different sessions and animals thus have to be aligned to each other and to a standardized brain coordinate system. Here, we evaluate two typical workflows for localization of individual electrodes in standardized coordinates. These workflows rely on imaging brains with fluorescent probe tracks and warping 3D image stacks to standardized brain atlases. One workflow is based on tissue clearing and selective plane illumination microscopy (SPIM), whereas the other workflow is based on serial block-face two-photon (SBF2P) microscopy. In both cases electrophysiological features are then used to anchor particular electrodes along the reconstructed tracks to specific locations in the brain atlas and therefore to specific brain structures. We performed groundtruth experiments, in which motor cortex outputs are labeled with ChR2 and a fluorescence protein. Light-evoked electrical activity and fluorescence can be independently localized. Recordings from brain regions targeted by the motor cortex reveal better than 0.1-mm accuracy for electrode localization, independent of workflow used.

hsci.harvard.edu

Scientists in the HSCI Skin Program are using stem cells to regenerate tissue without scarring.

chanzuckerberg.com

CZI is always looking for talented people to join us, with career opportunities across our science and education teams.

theethogram.com

Learn about the stunning true story of this marvel of the Scottish Highlands in the latest from Creature Feature!

vfce.arizona.edu

Welcome to the Valley Fever Center for Excellence’s website. Here we try to provide reliable and timely information about coccidioidomycosis, the medical name for Valley fever.