Les 10 concurrents jcda.ca les plus visités

jida.scholasticahq.com

JIDA aims is to provide good-quality information to support continuing education, professional development and best practice in Dentistry.

jpma.org.pk

Review articles highlighting importance of various issues in the domain of public health, drug and medical education

actamedindones.org

acta medica indonesiana

irjournal.org

Gut microbiota in pathophysiology, diagnosis, and therapeutics of inflammatory bowel disease

analesderadiologiamexico.com

anales de radiología, méxico. smri es el órgano oficial de la sociedad mexicana de radiología e imagen a.c.

iv.iiarjournals.org

Background/Aim: The role of senescence and bone marrow-derived cells in silica-induced pulmonary fibrosis is unknown. Materials and Methods: C57BL/6HNsd, p16+/LUC, and tdTOMp16+ mice were intratracheally injected with 200 mg/kg crystalline silica or irradiated (20 Gy) to the thoracic cavity and followed for the development of lung fibrosis. Results: The p16+/LUC mice demonstrated senescence by day 7 after silica exposure. C57BL/6 mice exposed to silica demonstrated upregulation of p16, p21, and tyrosine kinase Fgr by day 7, whereas thoracic irradiation induced p21 and Fgr by day 50 and p16 by day 110. Silica exposed GFP+ bone marrow chimeric C57BL/6 mice demonstrated senescent cells and gfp+/Fgr+ monocyte/macrophages in the lungs on day 21. The Fgr inhibitor TL02-59 abrogated monocyte/macrophages recruitment in in vitro transwell experiments. Conclusion: Both silica and radiation exposure induce senescence and upregulate tyrosine kinase Fgr for the recruitment of bone marrow-derived monocyte/macrophages and the development of pulmonary fibrosis.

ijsrd.com

ijsrd - international journal for scientific research & development is an india�s leading open-access peer reviewed international e-journal for science, engineering & technologies� manuscript.

ejomr.org

Porous titanium is used for the reconstruction of large bone defects due to its excellent mechanical strength. The quality of osseointegration of implants placed in bone reconstructed with porous titanium is unknown. The purpose of this in vivo study was to evaluate the osseointegration of implants at sites reconstructed using porous titanium.