Top 10 bioguider.com Wettbewerber

keyanhr.com

教育科研人才网（www.keyanhr.com）-面向海内外教学科研学者的高层次人才专业网站，为全国高校、科研机构发布高层次人才引进公告。

bio-equip.com

中国生物器材网是提供生物仪器、试剂、实验耗材、生物技术服务信息的专业信息平台，为生命科学、医学研究单位，大专院校，医院，疾控、生物工程，医药，检验检疫，农林，畜牧，食品，环保等行业提供最优质的互联网信息服务。

ebiotrade.com

生物通,专注生命科学研究进展

biosino.org

Accurate annotation of protein coding regions in mRNA is essential for understanding how genetic information is translated. We developed a deep neural network to directly predict and analyze translation initiation and termination sites from RNA sequences. Trained with annotated human mRNAs, our model learned hidden rules of translation control and achieved a near perfect prediction of translation sites across entire human transcriptome. Our model revealed a surprising role of codon usage in regulating translation termination, which was experimentally validated. We also identified thousands of new open reading frames in mRNAs or annotated lncRNAs, some of which were confirmed experimentally. Remarkably, the model trained with human mRNAs achieved high prediction accuracy in all eukaryotes and good prediction in the polycistronic transcripts from prokaryotes or RNA viruses, suggesting a high degree of conservation in translation control. Collectively, this study presents a general and efficient deep learning model for RNA translation, providing new insights into the complexity of translation regulation.

biosou.com

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biox.cn

中国生物学与医学科研门户，包括生物及医学领域的基础知识，最新研究进展和科普知识，提供博客服务和论坛交流。