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jrhm.org

A comprehensive review on reproductive toxicity of fenugreek and its bioactive component diosgenin: A review based on toxicological evidence

quantum-journal.org

Tom Krüger and Wolfgang Mauerer, Quantum 9, 1903 (2025). The Quantum Approximate Optimisation Algorithm (QAOA) is a widely studied quantum-classical iterative heuristic for combinatorial optimisation. While QAOA targets problems in complexity clas…

minervamedica.it

Correction to: The administration of S. salivarius K12 to children may reduce the rate of SARS-CoV-2 infection

sciencegate.app

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researchgate.net

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aeurologia.com

Introduction: The most common type of renal cancers is the clear cell renal cell carcinoma (CCRCC) and 98% of CCRCCs have a loss of sequence in the short arm of chromosome 3 by deletion or translocation. Programmed cell death; another possible mechanism of tumorigenesis, comprises two separate components: apoptosis and autophagy. This study aims to show the rela-tion between the prognostic parameters and survival, and Beclin-1, as the representative marker of autophagy, and Bcl-2 as the representative marker of apoptosis in CCRCC patients. In this study, we aimed to determine if Beclin-1 and Bcl-2 expression levels can provide any prognostic information about CCRCC patients.Methods: We examined a total of 84 patients who underwent partial or radical nephrectomy and were diagnosed as having CCRCC between January 2008 and December 2015. Immunohistochemical staining was performed, the evaluation was for Beclin-1 and Bcl-2 semi-quantitative, and based on the percentage of positively stained cells (proportion) and staining intensity. Results: There was only a statistical significance between Beclin-1 expression and age (r:-0.274; p=0.012; p Conclusion: There was only marginal correlation between Beclin-1 expression and ISUP grade. No other histopathologic prog-nostic parameters histologic parameters revealed any signigificance. The higher expression of Bcl-2 is correlated with nuclear lowe