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isa.ac.cn

中国科学院亚热带农业生态研究所自1978年任务建所以来，始终牢记使命，不断奋发进取，经过几代人的努力，为我国南方农业现代化道路的探索和亚热带区域农业可持续发展作出了重要贡献。特别是2002年进入中国科学院知识创新工程序列以来，在中国科学院“三个面向、四个率先”新的办院方针指引下，在“练内功卧薪尝胆，图创新众志成城”的研究所创新文化的引领下，围绕亚热带区域农业与生态环境协调发展的国家需求和地方经济建设，积极凝练学科方向和科学目标，强化农业生态研究平台建设，研究所快速发展成为有一定影响的亚热带区域农业生态领域的研究机构，为亚热带区域农业可持续发展与生态环境建设做出了卓越的贡献。

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pedologica.issas.ac.cn

土壤学报

scienceopen.com

Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the resulting coronavirus disease 2019 (Covid-19) have afflicted tens of millions of people in a worldwide pandemic. Safe and effective vaccines are needed urgently. Methods In an ongoing multinational, placebo-controlled, observer-blinded, pivotal efficacy trial, we randomly assigned persons 16 years of age or older in a 1:1 ratio to receive two doses, 21 days apart, of either placebo or the BNT162b2 vaccine candidate (30 μg per dose). BNT162b2 is a lipid nanoparticle–formulated, nucleoside-modified RNA vaccine that encodes a prefusion stabilized, membrane-anchored SARS-CoV-2 full-length spike protein. The primary end points were efficacy of the vaccine against laboratory-confirmed Covid-19 and safety. Results A total of 43,548 participants underwent randomization, of whom 43,448 received injections: 21,720 with BNT162b2 and 21,728 with placebo. There were 8 cases of Covid-19 with onset at least 7 days after the second dose among participants assigned to receive BNT162b2 and 162 cases among those assigned to placebo; BNT162b2 was 95% effective in preventing Covid-19 (95% credible interval, 90.3 to 97.6). Similar vaccine efficacy (generally 90 to 100%) was observed across subgroups defined by age, sex, race, ethnicity, baseline body-mass index, and the presence of coexisting conditions. Among 10 cases of severe Covid-19 with onset after the first dose, 9 occurred in placebo recipients and 1 in a BNT162b2 recipient. The safety profile of BNT162b2 was characterized by short-term, mild-to-moderate pain at the injection site, fatigue, and headache. The incidence of serious adverse events was low and was similar in the vaccine and placebo groups. Conclusions A two-dose regimen of BNT162b2 conferred 95% protection against Covid-19 in persons 16 years of age or older. Safety over a median of 2 mont

instrument.com.cn

由仪器信息网联合河北省检验检测学会共同主办的 2025年“万里行”—— 携手品牌合作伙伴走进药企、高校、检测机构（石家庄站）， 活动圆满落下帷幕。

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